Mod Manager Settings: You might also see the SKYUI Error Code 1 on your computer if you have misconfigured some of the Mod Manager settings on your computer.Faulty Installation: It is possible that either the game, the SKYSE, or the mods haven’t been properly installed on your computer due to which you are facing this error while trying to launch the game with mods and SkyrimSE is unable to load.Therefore, it is recommended that you provide administrative permissions to the game.